Free shipping on all orders in the USA!

Effect of Metformin and Pioglitazone on Treatment of Psoriasis

ISBN: 9783330029453
Publisher: LAP LAMBERT Academic Publishing
Publication Date: 2017-01-13
Number of pages: 56
  • Sale
  • Regular price $53.74

Any used item that originally included an accessory such as an access code, one time use worksheet, cd or dvd, or other one time use accessories may not be guaranteed to be included or valid. By purchasing this item you acknowledge the above statement.

Description


Psoriasis vulgaris is a common, chronic, relapsing skin disease characterized by predominant involvement of skin, nails and joints. Recent advances in its pathophysiology have shifted the notion of psoriasis from that of a 'disease of the skin' to a 'T-cell mediated systemic disease'. Metformin acts as a modulator of the immune system, in psoriatic patients and has a remarkable effect on the early stages of psoriasis. The activation of PPAR-γ by pioglitazone results in a reduction of the formation of the proinflammatory cytokines, and the inflammatory cells infiltration. These findings support the potential use of PPAR-γ ligands as therapeutic agents in the therapy of conditions associated with autoimmune disease.

Customer Reviews


MORE FROM THIS COLLECTION